GenAge entry for Gpx4 (Mus musculus)
Gene information (ID: 324)
- Symbol
- Gpx4
- Aliases
- PHGPx; snGPx; mtPHGPx; 1700027O09Rik
- Name
- Glutathione peroxidase 4
- Organism
- Mus musculus (AnAge)
- Known functions and activities
- Detoxification of oxidative damage to membrane lipids
Potential relevance to longevity and/or ageing
- Observations
- Heterozygous knockouts have a 7% increase in median lifespan.
- % change in avg or median lifespan
- Median lifespan is 7% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Knockout
- Longevity Category
- Anti-Longevity
- Primary reference
-
In other databases
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as GPX4
- LongevityMap
- A homolog of this gene for Homo sapiens is present as GPX4
Homologs in other organisms
- Danio rerio
- gpx4b
- Danio rerio
- gpx4a
- Homo sapiens
- GPX4
- Rattus norvegicus
- Gpx4
- Saccharomyces cerevisiae
- HYR1
- Saccharomyces cerevisiae
- GPX1
- Schizosaccharomyces pombe
- gpx1
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (625249)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar