GenAge entry for Fxn (Mus musculus)
Gene information (ID: 290)
- Symbol
- Fxn
- Aliases
- FA; X25; FARR; Frda
- Name
- frataxin
- Organism
- Mus musculus (AnAge)
- Known functions and activities
- Regulation of mitochondrial iron transport and respiration
Potential relevance to longevity and/or ageing
- Observations
- Disruption results in reduced lifespan, increased oxidative stress, impaired respiration, and the development of hepatic tumors.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Knockout
- Longevity Category
- Pro-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- CellAge
- A homolog of this gene for Homo sapiens is present as FXN
Homologs in other organisms
- Caenorhabditis elegans
- frh-1
- Danio rerio
- fxn
- Homo sapiens
- FXN
- Rattus norvegicus
- Fxn
- Saccharomyces cerevisiae
- YFH1
- Schizosaccharomyces pombe
- SPCC1183.03c
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (14297)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar