Caenorhabditis elegansGenAge entry for CELE_F59C6.5 (Caenorhabditis elegans)

Gene information (ID: 277)

Symbol
CELE_F59C6.5
Name
Protein F59C6.5
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Subunit of the NADH:ubiquinone oxidoreductase complex

Potential relevance to longevity and/or ageing

Observations
RNA interference in adulthood extended mean lifespan by 19%.
% change in avg or median lifespan
Average lifespan is 19% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNAi resulted in a 16% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 16% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference
      Observations
      Post developmental RNAi resulted in a 30-70% mean lifespan extension (depending on background).
      % change in avg or median lifespan
      Average lifespan is 70% higher.
      Lifespan Effect
      Increase
      Genetic Manipulation
      RNA interference
      Longevity Category
      Anti-Longevity
      Primary reference

        Homologs in other organisms

        Danio rerio
        ndufb10
        Drosophila melanogaster
        Pdsw
        Homo sapiens
        NDUFB10
        Mus musculus
        Ndufb10
        Rattus norvegicus
        Ndufb10

        External links

        WormBase
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        Ensembl
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        Entrez Gene
        View on Entrez Gene database (172933)
        Homologues
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        UniProt
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        Internet
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