Caenorhabditis elegansGenAge entry for CELE_F59C6.5 (Caenorhabditis elegans)

Gene information (ID: 277)

Symbol
CELE_F59C6.5
Name
Protein F59C6.5
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Subunit of the NADH:ubiquinone oxidoreductase complex

Potential relevance to longevity and/or ageing

Observations
RNA interference in adulthood extended mean lifespan by 19%.
% change in avg or median lifespan
Average lifespan is 19% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNAi resulted in a 16% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 16% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference
      Observations
      Post developmental RNAi resulted in a 30-70% mean lifespan extension (depending on background).
      % change in avg or median lifespan
      Average lifespan is 70% higher.
      Lifespan Effect
      Increase
      Genetic Manipulation
      RNA interference
      Longevity Category
      Anti-Longevity
      Primary reference

        In other databases

        GenAge microarray genes
        • A homolog of this gene for Homo sapiens is present as NDUFB10

        Homologs in other organisms

        Danio rerio
        ndufb10
        Drosophila melanogaster
        Pdsw
        Homo sapiens
        NDUFB10
        Mus musculus
        Ndufb10
        Rattus norvegicus
        Ndufb10

        External links

        WormBase
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        Ensembl
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        Entrez Gene
        View on Entrez Gene database (172933)
        Homologues
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        UniProt
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        Internet
        Search Google or Search Google Scholar