Caenorhabditis elegansGenAge entry for CELE_F11A3.2 (Caenorhabditis elegans)

Gene information (ID: 925)

Symbol
CELE_F11A3.2
Name
hypothetical protein
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Inhibition of eIF2B /F11A3.2 during adulthood conferred thermal and oxidative stress resistance and reduced the fecundity and fat storage. Mean LS was increased by 14%.
% change in avg or median lifespan
Average lifespan is 14% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference post development
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    eif2b4
    Drosophila melanogaster
    eIF2B-delta
    Homo sapiens
    EIF2B4
    Mus musculus
    Eif2b4
    Rattus norvegicus
    Eif2b4
    Saccharomyces cerevisiae
    GCD2

    External links

    WormBase
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    Entrez Gene
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    Homologues
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    UniProt
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    Internet
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