Caenorhabditis elegansGenAge entry for C28H8.11 (Caenorhabditis elegans)

Gene information (ID: 1842)

Symbol
C28H8.11
Name
Protein C28H8.11
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Knockdown of tdo-2 in both WT animals and animals expressing a-synuclein resulted in an extension of both the median and mean lifespan of ~15%.
% change in avg or median lifespan
Average lifespan is 15% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    tdo2b
    Danio rerio
    tdo2a
    Drosophila melanogaster
    v
    Homo sapiens
    TDO2
    Mus musculus
    Tdo2
    Rattus norvegicus
    Tdo2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (175836)
    Homologues
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    UniProt
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    Internet
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