Caenorhabditis elegansGenAge entry for C11H1.3 (Caenorhabditis elegans)

Gene information (ID: 60)

Symbol
C11H1.3
Name
Protein C11H1.3
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
E3 ubiquitin ligase

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 10% in wild type animals, 14% in a daf-2 background and 41% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 10% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    mgrn1a
    Danio rerio
    RNF157
    Danio rerio
    mgrn1b
    Drosophila melanogaster
    CG9941
    Homo sapiens
    RNF157
    Homo sapiens
    MGRN1
    Mus musculus
    Mgrn1
    Mus musculus
    Rnf157
    Rattus norvegicus
    Rnf157
    Rattus norvegicus
    Mgrn1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (181537)
    Homologues
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    UniProt
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    Internet
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