GenAge entry for Atg5 (Mus musculus)
Gene information (ID: 1862)
- Symbol
- Atg5
- Name
- autophagy related 5
- Organism
- Mus musculus (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Overexpression of Atg5 extends median lifespan of mice by 17.2%. Additionally, it enhances autophagy, and Atg5 transgenic mice show anti-ageing phenotypes, including leanness, increased insulin sensitivity and improved motor function.
- % change in avg or median lifespan
- Median lifespan is 17% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as ATG5
- CellAge
- A homolog of this gene for Homo sapiens is present as ATG5
Homologs in other organisms
- Caenorhabditis elegans
- atg-5
- Danio rerio
- atg5
- Drosophila melanogaster
- Atg5
- Homo sapiens
- ATG5
- Rattus norvegicus
- Atg5
- Saccharomyces cerevisiae
- ATG5
- Schizosaccharomyces pombe
- atg5
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (11793)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar