Caenorhabditis elegans GenDR Dietary Restriction Gene Manipulation: rheb-1

Gene Information (Entrez Gene ID: 176327)

Symbol
rheb-1
Name
RHEB (Ras Homolog Enriched in Brain) hom
Organism
Caenorhabditis elegans (AnAge)
Entrez Gene ID
176327

Potential relevance to dietary restriction and ageing

Observations

rheb-1 RNAi extends lifespan by mimicking the DR effect. Under ad lib conditions, rheb-1 RNAi extends lifespan by 19.1% and the longevity-promoting effects of two DR regimens solid DR and intermittent fasting are abolished [2566].

References

    In other databases

    GenAge model organism genes
    • This gene is present as rheb-1
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as RHEB

    Homologs

    Danio rerio
    rhebl1
    Danio rerio
    rheb
    Drosophila melanogaster
    Rheb
    Homo sapiens
    RHEB
    Homo sapiens
    RHEBL1
    Mus musculus
    Rheb
    Mus musculus
    Rhebl1
    Rattus norvegicus
    Rhebl1
    Rattus norvegicus
    Rheb
    Saccharomyces cerevisiae
    RHB1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    ID 176327
    Homologues
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    UniProt
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    Internet
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