Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: ISW2

Gene Information (Entrez Gene ID: 854480)

Symbol
ISW2
Name
Isw2p
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
854480

Potential relevance to dietary restriction and ageing

Observations

Under normal conditions, deletion of ISW2 in yeast extends replicative lifespan by 24%. Lifespan is also extended by limiting glucose concentrations in the diet to either 0.5% or 0.05%, however, these CR conditions are not able to extend lifespan when ISW2 is deleted, instead shortening lifespan.

References

    In other databases

    GenAge model organism genes
    • This gene is present as ISW2

    Homologs

    Danio rerio
    smarca5
    Homo sapiens
    SMARCA5
    Homo sapiens
    SMARCA1
    Mus musculus
    Smarca5
    Mus musculus
    Smarca1
    Rattus norvegicus
    Smarca1
    Rattus norvegicus
    Smarca5

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 854480
    Homologues
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    UniProt
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    Internet
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