GenDR Dietary Restriction Gene Manipulation: GUP1
Gene Information (Entrez Gene ID: 852796)
Potential relevance to dietary restriction and ageing
- Observations
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GUP1 deletion extends mean and maximum replicative lifespan by 32 and 30%, respectively, as well as chronological lifespan. DR-induced maximal replicative lifespan extension is not further increased by GUP1 deletion, while gup1 mutant displayed slightly longer chronological lifespan under DR [2581].
- References
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In other databases
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as hhat-2
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as HHAT
Homologs
- Caenorhabditis elegans
- hhat-1
- Caenorhabditis elegans
- hhat-2
- Danio rerio
- hhat
- Danio rerio
- hhatla
- Danio rerio
- hhatlb
- Drosophila melanogaster
- rasp
- Homo sapiens
- HHAT
- Homo sapiens
- HHATL
- Mus musculus
- Hhat
- Mus musculus
- Hhatl
- Rattus norvegicus
- Hhat
- Rattus norvegicus
- Hhatl
External links
- Saccharomyces Genome Database
- Search
- Ensembl
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- Entrez Gene
- ID 852796
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar