GenDR Dietary Restriction Gene Manipulation: YHB4
Gene Information (Entrez Gene ID: 853149)
- Yeast HemogloBin-like protein 4
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
Potential relevance to dietary restriction and ageing
sfa1;yhb1 double mutant cancels out the ability of moderate DR to extend replicative lifespan, but not chronological lifespan. Deleting YHB1 partially abolished DR-induced replicative lifespan extension, whereas deleting SFA1 alone had no effect. Yhb1 and Sfa1 may play redundant roles .
- Schizosaccharomyces pombe