Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: VPS21

Gene Information (Entrez Gene ID: 854256)

Symbol
VPS21
Aliases
VPS12 VPT12 YPT21 YPT51
Name
Vacuolar Protein Sorting 21
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
854256

Potential relevance to dietary restriction and ageing

Observations

Lack of VPS21 reduces lifespan under starvation conditions to a level similar to that of wild-type cells incubated in synthetic complete medium and therefore blocked the lifespan-extending effect of DR [2500].

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as rab-5
    • This gene is present as VPS21

    Homologs

    Caenorhabditis elegans
    rab-21
    Caenorhabditis elegans
    rab-5
    Danio rerio
    rab24
    Danio rerio
    rab20
    Danio rerio
    rab22a
    Danio rerio
    RAB31
    Danio rerio
    RAB21
    Danio rerio
    rab5b
    Danio rerio
    rab5aa
    Danio rerio
    rab5c
    Danio rerio
    rab5ab
    Drosophila melanogaster
    RabX1
    Drosophila melanogaster
    Rab5
    Drosophila melanogaster
    Rab21
    Homo sapiens
    RAB22A
    Homo sapiens
    0
    Homo sapiens
    RAB17
    Homo sapiens
    RAB20
    Homo sapiens
    RAB31
    Homo sapiens
    RAB24
    Homo sapiens
    RAB5C
    Homo sapiens
    RAB5B
    Homo sapiens
    RAB21
    Homo sapiens
    RAB5A
    Mus musculus
    Rab20
    Mus musculus
    Rab17
    Mus musculus
    Rab22a
    Mus musculus
    Rab5c
    Mus musculus
    Rab31
    Mus musculus
    Rab5b
    Mus musculus
    Rab21
    Mus musculus
    Rab24
    Mus musculus
    Rab5a
    Rattus norvegicus
    AABR07009572.1
    Rattus norvegicus
    Rab5c
    Rattus norvegicus
    Rab24
    Rattus norvegicus
    Rab31
    Rattus norvegicus
    Rab5a
    Rattus norvegicus
    Rab5b
    Rattus norvegicus
    Rab21
    Rattus norvegicus
    Rab17
    Rattus norvegicus
    Rab22a
    Rattus norvegicus
    Rab24
    Rattus norvegicus
    Rab20

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 854256
    Homologues
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    UniProt
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    Internet
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