LongevityMap variant
- Longevity Association
- Significant
- Population
- American (Caucasian)
- Study Design
- Genome-wide association study in 801 centenarians and 914 healthy controls
- Conclusions
- 281 SNPs were found to discriminate between cases and controls
- HGNC symbol
- ENOX1
- Aliases
- CNOX; PIG38; cCNOX; bA64J21.1
- Common name
- ecto-NOX disulfide-thiol exchanger 1
- Description
- The protein encoded by this gene is involved in plasma membrane electron transport pathways. The encoded protein has both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity. The two activities cycle with a periodicity of 24 minutes, with one activity being at its peak when the other is at its lowest. [provided by RefSeq, Dec 2016]
- Other longevity studies of this gene
- 1
- OMIM
- 610914
- Ensembl
- ENSG00000120658
- UniProt/Swiss-Prot
- A0A024RDT8_HUMAN
- Entrez Gene
- 55068
- UniGene
- 128258
- HapMap
- View on HapMap
Homologs in model organisms
- Danio rerio
- enox1
- Drosophila melanogaster
- CG10948
- Mus musculus
- Enox1
- Rattus norvegicus
- Enox1
Sebastiani et al. (2012)
Other variants which are also part of this study
