LongevityMap Gene
Gene details
- HGNC symbol
- ULK1
- Aliases
- ATG1; ATG1A; UNC51; hATG1; Unc51.1
- Common name
- unc-51 like autophagy activating kinase 1
- Description
- Cytogenetic Location
- 12q24.33
- UCSC Genome Browser
- View 12q24.33 on the UCSC genome browser
- OMIM
- 603168
- Ensembl
- ENSG00000177169
- UniProt/Swiss-Prot
- ULK1_HUMAN
- Entrez Gene
- 8408
- UniGene
- 47061
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- unc-51
- Danio rerio
- ulk1b
- Danio rerio
- ulk1a
- Drosophila melanogaster
- Atg1
- Mus musculus
- Ulk1
- Rattus norvegicus
- Ulk1
- Saccharomyces cerevisiae
- ATG1
In other databases
- GenAge model organism genes
- GenDR gene manipulations
Studies (1)
Significant/Non-significant: 1/0
- Longevity Association
- Significant
- Population
- Dutch
- Study Design
- 1,018 SNPs within a 10-kb window around 40 mTOR signalling genes were studied for differences in variation between 417 unrelated nonagenarian participants and 476 younger controls
- Conclusions
- As a whole, there was a significant association of genetic variation in the mTOR pathway and familial longevity, though no individual gene was significant after correcting for multiple hypothesis testing
- Indentifier
- ULK1
- Reference