LongevityMap Gene
Gene details
- HGNC symbol
- RPA1
- Aliases
- HSSB; RF-A; RP-A; REPA1; RPA70; MST075
- Common name
- replication protein A1
- Description
- Cytogenetic Location
- 17p13.3
- UCSC Genome Browser
- View 17p13.3 on the UCSC genome browser
- OMIM
- 179835
- Ensembl
- ENSG00000132383
- UniProt/Swiss-Prot
- RFA1_HUMAN
- Entrez Gene
- 6117
- UniGene
- 461925
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- rpa-1
- Danio rerio
- rpa1
- Drosophila melanogaster
- RpA-70
- Mus musculus
- Rpa1
- Rattus norvegicus
- Rpa1
- Saccharomyces cerevisiae
- RFA1
- Schizosaccharomyces pombe
- ssb1
In other databases
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as rpa-1
- GenAge human genes
- This gene is present as RPA1
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Danish
- Study Design
- 592 SNPs from 77 genes involved in nine sub-processes were analyzed in 1089 long-lived and 736 middle-aged Danes. Then, a replicated study was carried out in a German cohort.
- Conclusions
- The results did not remain significant after correction. The findings drawn from the Danish cohort were not replicated in German samples.
- Indentifier
- rs5030740
- Reference