LongevityMap Gene
Gene details
- HGNC symbol
- PERP
- Aliases
- THW; KCP1; PIGPC1; KRTCAP1; dJ496H19.1
- Common name
- PERP, TP53 apoptosis effector
- Description
- Cytogenetic Location
- 6q23.3
- UCSC Genome Browser
- View 6q23.3 on the UCSC genome browser
- OMIM
- 609301
- Ensembl
- ENSG00000112378
- UniProt/Swiss-Prot
- PERP_HUMAN
- Entrez Gene
- 64065
- UniGene
- 201446
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
In other databases
- CellAge gene expression
- This gene is present as PERP
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- German
- Study Design
- Targeted investigation of 500 SNPs in 343 selected genes associated with longevity in model systems. A sample of 386 unrelated German centenarians (mean age: 101.3 years) and 410 control subjects (mean age: 66.6 years) were studied.
- Conclusions
- No significant associations were found after correcting for multiple testing, though three SNPs (rs770087, rs2301582 and rs648802 in, respectively, DUSP6, NALP1 and PERP) had a suggestive association. This association was not confirmed in an independent French collection of 541 centenarians and 469 younger controls.
- Indentifier
- rs648802
- Reference