LongevityMap Gene
Gene details
- HGNC symbol
- NCAPD2
- Aliases
- CNAP1; CAP-D2; hCAP-D2
- Common name
- non-SMC condensin I complex subunit D2
- Description
- Cytogenetic Location
- 12p13.31
- UCSC Genome Browser
- View 12p13.31 on the UCSC genome browser
- OMIM
- 615638
- Ensembl
- ENSG00000010292
- UniProt/Swiss-Prot
- B3KMS0_HUMAN
- Entrez Gene
- 9918
- UniGene
- 5719
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- dpy-28
- Danio rerio
- ncapd2
- Drosophila melanogaster
- Cap-D2
- Mus musculus
- Ncapd2
- Rattus norvegicus
- Ncapd2
- Saccharomyces cerevisiae
- YCS4
- Schizosaccharomyces pombe
- cnd1
In other databases
- CellAge gene expression
- This gene is present as NCAPD2
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- American (Caucasian)
- Study Design
- Genome-wide association study for longevity-related traits in up to 1345 Framingham Study participants from 330 families; 713 participants achieved age 65 years or greater. A total of 79 potential candidate genes and regions associated with longevity were also studied.
- Conclusions
- Although no genome-wide associations were significant, several SNPs in some previously associated genes with longevity had suggestive associations with age at death or morbidity-free survival at age 65 years. Noteworthy results included two SNPs within FOXO1A (rs10507486 and rs4943794) associated with age at death.
- Indentifier
- rs4764600
- Reference