LongevityMap Gene
Gene details
- HGNC symbol
- NAAA
- Aliases
- PLT; ASAHL
- Common name
- N-acylethanolamine acid amidase
- Description
- This gene encodes an N-acylethanolamine-hydrolyzing enzyme which is highly similar to acid ceramidase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Cytogenetic Location
- 4q21.1
- UCSC Genome Browser
- View 4q21.1 on the UCSC genome browser
- OMIM
- 607469
- Ensembl
- ENSG00000138744
- UniProt/Swiss-Prot
- NAAA_HUMAN
- Entrez Gene
- 27163
- UniGene
- 437365
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
In other databases
- GenAge microarray genes
- This gene is present as NAAA
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- American, English, Irish
- Study Design
- 10 late-onset Alzheimer's disease genes were tested for association with human aging in the dataset (1385 samples with documented age at death, age range: 58–108 years; mean age at death: 80.2 years) using the most significant SNPs found in the previous studies. A set of 41 tentative SNPs span the genome were identified in this study.
- Conclusions
- Some signals were at best tentative but may merit study in larger sample sets
- Indentifier
- rs10518142
- Reference