LongevityMap Gene
Gene details
- HGNC symbol
- KIF26B
- Aliases
- Common name
- kinesin family member 26B
- Description
- The protein encoded by this gene is an intracellular motor protein thought to transport organelles along microtubules. The encoded protein is required for kidney development. Elevated levels of this protein have been found in some breast and colorectal cancers. [provided by RefSeq, Mar 2017]
- Cytogenetic Location
- 1q44
- UCSC Genome Browser
- View 1q44 on the UCSC genome browser
- OMIM
- 614026
- Ensembl
- ENSG00000162849
- UniProt/Swiss-Prot
- B7WPD9_HUMAN
- Entrez Gene
- 55083
- UniGene
- 143134
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- vab-8
- Danio rerio
- kif26ba
- Drosophila melanogaster
- CG14535
- Mus musculus
- Kif26b
- Rattus norvegicus
- Kif26b
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- German
- Study Design
- Genome-wide association study comparing 664,472 autosomal SNPs in 763 long-lived individuals (mean age: 99.7 years) and 1085 controls (mean age: 60.2 years). Top SNPs from the GWAS were further investigated in an independent German sample comprised of 754 long-lived individuals (mean age: 96.9 years) and 860 controls (mean age: 67.3 years).
- Conclusions
- Thirty-two SNPs previously associated with longevity were not associated with longevity in this study
- Indentifier
- rs10924270
- Reference