LongevityMap Gene

Gene details

HGNC symbol
HLA-DPB2 
Aliases
DP2B; DPB2; DPbeta2; HLA-DP2B 
Common name
major histocompatibility complex, class II, DP beta 2 (pseudogene) 
Description
Cytogenetic Location
6p21.32
UCSC Genome Browser
View 6p21.32 on the UCSC genome browser
OMIM
Ensembl
ENSG00000224557
UniProt/Swiss-Prot
Entrez Gene
3116
UniGene
665450
1000 Genomes
1000 Genomes

Homologs in model organisms

No homologs found

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
German
Study Design
Genome-wide association study comparing 664,472 autosomal SNPs in 763 long-lived individuals (mean age: 99.7 years) and 1085 controls (mean age: 60.2 years). Top SNPs from the GWAS were further investigated in an independent German sample comprised of 754 long-lived individuals (mean age: 96.9 years) and 860 controls (mean age: 67.3 years).
Conclusions
Thirty-two SNPs previously associated with longevity were not associated with longevity in this study
Indentifier
rs4713607
Reference