LongevityMap Gene
Gene details
- HGNC symbol
- HLA-DPB2
- Aliases
- DP2B; DPB2; DPbeta2; HLA-DP2B
- Common name
- major histocompatibility complex, class II, DP beta 2 (pseudogene)
- Description
- Cytogenetic Location
- 6p21.32
- UCSC Genome Browser
- View 6p21.32 on the UCSC genome browser
- OMIM
- Ensembl
- ENSG00000224557
- UniProt/Swiss-Prot
- Entrez Gene
- 3116
- UniGene
- 665450
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
No homologs found
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- German
- Study Design
- Genome-wide association study comparing 664,472 autosomal SNPs in 763 long-lived individuals (mean age: 99.7 years) and 1085 controls (mean age: 60.2 years). Top SNPs from the GWAS were further investigated in an independent German sample comprised of 754 long-lived individuals (mean age: 96.9 years) and 860 controls (mean age: 67.3 years).
- Conclusions
- Thirty-two SNPs previously associated with longevity were not associated with longevity in this study
- Indentifier
- rs4713607
- Reference