LongevityMap Gene
Gene details
- HGNC symbol
- GDPD3
- Aliases
- GDE7
- Common name
- glycerophosphodiester phosphodiesterase domain containing 3
- Description
- Cytogenetic Location
- 16p11.2
- UCSC Genome Browser
- View 16p11.2 on the UCSC genome browser
- OMIM
- 616318
- Ensembl
- ENSG00000102886
- UniProt/Swiss-Prot
- GDPD3_HUMAN
- Entrez Gene
- 79153
- UniGene
- 289015
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Danio rerio
- gdpd3b
- Danio rerio
- gdpd3a
- Mus musculus
- Gdpd3
- Rattus norvegicus
- Gdpd3
- Schizosaccharomyces pombe
- SPAC4D7.02c
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Italian (Southern)
- Study Design
- A two-stage case-control study was performed to identify the association between longevity and variation of in homeostasis regulation pathway genes. 317 SNPs in 104 genes were analyzed in 78 cases (≥90 years, median age 98 years, 42 females) and 71 controls (<90 years, median age 67 years, 32 females) in stage 1. Then, 31 candidate SNPs identified in stage 1 (π markers = 0.1) were analyzed in an independent sample composed by 288 cases (≥90 years, median age 92 years, 163 females) and 554 controls (<90 years, median age 67 years, 277 females).
- Conclusions
- After adjustment for multiple testing, no significant association was identified between various SNPs and longevity.
- Indentifier
- rs12444415
- Reference