LongevityMap Gene
Gene details
- HGNC symbol
- FGD5
- Aliases
- ZFYVE23
- Common name
- FYVE, RhoGEF and PH domain containing 5
- Description
- Cytogenetic Location
- 3p25.1
- UCSC Genome Browser
- View 3p25.1 on the UCSC genome browser
- OMIM
- 614788
- Ensembl
- ENSG00000154783
- UniProt/Swiss-Prot
- B7ZM68_HUMAN
- Entrez Gene
- 152273
- UniGene
- 412406
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- German
- Study Design
- Genome-wide association study comparing 664,472 autosomal SNPs in 763 long-lived individuals (mean age: 99.7 years) and 1085 controls (mean age: 60.2 years). Top SNPs from the GWAS were further investigated in an independent German sample comprised of 754 long-lived individuals (mean age: 96.9 years) and 860 controls (mean age: 67.3 years).
- Conclusions
- Thirty-two SNPs previously associated with longevity were not associated with longevity in this study
- Indentifier
- rs294636
- Reference