LongevityMap Gene
Gene details
- HGNC symbol
- ACSS3
- Aliases
- Common name
- acyl-CoA synthetase short-chain family member 3
- Description
- Cytogenetic Location
- 12q21.31
- UCSC Genome Browser
- View 12q21.31 on the UCSC genome browser
- OMIM
- 614356
- Ensembl
- ENSG00000111058
- UniProt/Swiss-Prot
- A0A0B4J1R2_HUMAN
- Entrez Gene
- 79611
- UniGene
- 259559
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Danio rerio
- acss3
- Drosophila melanogaster
- CG6432
- Mus musculus
- Acss3
- Rattus norvegicus
- Acss3
- Saccharomyces cerevisiae
- ACS2
In other databases
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as ACS2
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- American (Caucasian)
- Study Design
- Genome-wide association study for longevity-related traits in up to 1345 Framingham Study participants from 330 families; 713 participants achieved age 65 years or greater. A total of 79 potential candidate genes and regions associated with longevity were also studied.
- Conclusions
- Although no genome-wide associations were significant, mutiple SNPs and genes had suggestive associations with both age at death and morbidity-free survival at age 65 years
- Indentifier
- rs10506274
- Reference