GenDR Dietary Restriction Gene Manipulation: ubc-18
Gene Information (Entrez Gene ID: 175985)
- Symbol
- ubc-18
- Name
- UBiquitin Conjugating enzyme 18
- Organism
- Caenorhabditis elegans (AnAge)
- Entrez Gene ID
- 175985
Potential relevance to dietary restriction and ageing
- Observations
-
ubc-18 overexpression is unable to extend lifespan. Loss of ubc-18 function by mutation or RNAi reduces lifespan at 25 degree Celsius, but only slightly at 20 degree Celsius. RNAi depletion of ubc-18 completely suppresses increased longevity of eat-2 mutants [2572].
- References
-
Homologs
- Danio rerio
- ube2l3a
- Danio rerio
- ube2l3b
- Drosophila melanogaster
- Ubc84D
- Drosophila melanogaster
- CG17030
- Drosophila melanogaster
- Ubc10
- Homo sapiens
- UBE2L3
- Homo sapiens
- UBE2L5P
- Mus musculus
- Ube2l3
- Mus musculus
- Ube2l3
- Saccharomyces cerevisiae
- UBC5
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- ID 175985
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar