Caenorhabditis elegans GenDR Dietary Restriction Gene Manipulation: ire-1

Gene Information (Entrez Gene ID: 174305)

Symbol
ire-1
Name
IRE1 kinase related 1
Organism
Caenorhabditis elegans (AnAge)
Entrez Gene ID
174305

Potential relevance to dietary restriction and ageing

Observations

ire-1 mutation reduces slightly the lifespan under ad lib, but reduces significantly the lifespan extension by DR. ire-1 mutant has a significantly reduced slope in mean lifespan versus food concentrations relative to wild-type [2571].

References

    In other databases

    GenAge model organism genes
    • This gene is present as ire-1
    • A homolog of this gene for Drosophila melanogaster is present as Ire1
    GenDR gene manipulations
    • A homolog of this gene for Drosophila melanogaster is present as Ire1
    • A homolog of this gene for Saccharomyces cerevisiae is present as IRE1

    Homologs

    Drosophila melanogaster
    Ire1
    Saccharomyces cerevisiae
    IRE1
    Schizosaccharomyces pombe
    ppk4

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    ID 174305
    Homologues
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    UniProt
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    Internet
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