GenDR Dietary Restriction Gene Manipulation: kgb-1
Gene Information (Entrez Gene ID: 176866)
Potential relevance to dietary restriction and ageing
Loss-of-function kgb-1 mutant or inhibition of kgb-1 by post-developmental RNA interference reduces the lifespan extension of intermitent fasting. In the wild-type N2 worms, intermitent fasting increases lifespan by ~77%, while in the kgb-1 mutants lifespan extension is reduced to 23-24%.
No homologs found