LongevityMap Gene
Gene details
- HGNC symbol
- ZNF19
- Aliases
- KOX12
- Common name
- zinc finger protein 19
- Description
- The protein encoded by this gene contains a zinc finger, a nucleic acid-binding domain present in many transcription factors. This gene is located in a region next to ZNF23, a gene also encoding a zinc finger protein, on chromosome 16. [provided by RefSeq, Jul 2008]
- Cytogenetic Location
- 16q22.2
- UCSC Genome Browser
- View 16q22.2 on the UCSC genome browser
- OMIM
- 194525
- Ensembl
- ENSG00000157429
- UniProt/Swiss-Prot
- ZNF19_HUMAN
- Entrez Gene
- 7567
- UniGene
- 660076
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
No homologs found
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Caucasians
- Study Design
- Meta-analysis of GWAS in Caucasians from four prospective cohort studies: the Age, Gene/Environment Susceptibility-Reykjavik Study, the Cardiovascular Health Study, the Framingham Heart Study, and the Rotterdam Study participating in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Longevity was defined as survival to age 90 years or older (n = 1,836); the comparison group comprised cohort members who died between the ages of 55 and 80 years (n = 1,955).
- Conclusions
- There were 273 single-nucleotide polymorphism (SNP) associations with p < .0001, but none reached significance after correcting for multiple testing
- Indentifier
- rs12935091
- Reference