LongevityMap Gene
Gene details
- HGNC symbol
- TRANK1
- Aliases
- LBA1
- Common name
- tetratricopeptide repeat and ankyrin repeat containing 1
- Description
- Cytogenetic Location
- 3p22.2
- UCSC Genome Browser
- View 3p22.2 on the UCSC genome browser
- OMIM
- Ensembl
- ENSG00000168016
- UniProt/Swiss-Prot
- TRNK1_HUMAN
- Entrez Gene
- 9881
- UniGene
- 170999
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Italian
- Study Design
- Genome-wide association study on 410 long-living individuals (age range, 90–109 years) and 553 young control individuals (age range, 18–48 years) using 318,237 SNPs. An independent population with 116 long-lived individuals and 160 controls was used for replication purposes.
- Conclusions
- A total of 67 SNPs were identified with an indication of potentially being associated with longevity (p < 1 × 10−4), though 66 were not further validated
- Indentifier
- rs6769400
- Reference