LongevityMap Gene
Gene details
- HGNC symbol
- SVEP1
- Aliases
- CCP22; SELOB; SEL-OB; C9orf13; POLYDOM
- Common name
- sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
- Description
- Cytogenetic Location
- 9q31.3
- UCSC Genome Browser
- View 9q31.3 on the UCSC genome browser
- OMIM
- 611691
- Ensembl
- ENSG00000165124
- UniProt/Swiss-Prot
- B3KQM1_HUMAN
- Entrez Gene
- 79987
- UniGene
- 522334
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Danio rerio
- uncharacterized_F1QM
- Drosophila melanogaster
- uif
- Mus musculus
- Svep1
- Rattus norvegicus
- Svep1
Studies (1)
Significant/Non-significant: 1/0
- Longevity Association
- Significant
- Population
- American (Caucasian)
- Study Design
- Genome-wide association study using 1,471 genotyped participants from the Framingham Heart Study, of which 1,173 individuals had known lifespans, plus 517 individuals from the Offspring cohort for validating connections between longevity and genetic variants
- Conclusions
- A total of 27 SNPs, including in CDH4, SVEP1, CACNA1C, CARS, STK24, C7orf50, PARVG, NCAM2, PPP2R2C, NLRC5, BTBD9, RAC2, TGFA, KIAA0649, ABCC4, CLSTN2, FAM19A5 and RUNX3, were identified at the intersection of various statistical procedures
- Indentifier
- rs1327533
- Reference