LongevityMap Gene
Gene details
- HGNC symbol
- SLC6A7
- Aliases
- PROT
- Common name
- solute carrier family 6 member 7
- Description
- This gene is a member of the gamma-aminobutyric acid (GABA) neurotransmitter gene family and encodes a high-affinity mammalian brain L-proline transporter protein. This transporter protein differs from other sodium-dependent plasma membrane carriers by its pharmacological specificity, kinetic properties, and ionic requirements. [provided by RefSeq, Jul 2008]
- Cytogenetic Location
- 5q32
- UCSC Genome Browser
- View 5q32 on the UCSC genome browser
- OMIM
- 606205
- Ensembl
- ENSG00000011083
- UniProt/Swiss-Prot
- SC6A7_HUMAN
- Entrez Gene
- 6534
- UniGene
- 241597
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
Studies (1)
Significant/Non-significant: 1/0
- Longevity Association
- Significant
- Population
- American (Caucasian)
- Study Design
- Genome-wide association study in 801 centenarians and 914 healthy controls
- Conclusions
- 281 SNPs were found to discriminate between cases and controls
- Indentifier
- rs11954180
- Reference