LongevityMap Gene
Gene details
- HGNC symbol
- SEMA6A
- Aliases
- VIA; SEMA; HT018; SEMAQ; SEMA6A1
- Common name
- semaphorin 6A
- Description
- The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011]
- Cytogenetic Location
- 5q23.1
- UCSC Genome Browser
- View 5q23.1 on the UCSC genome browser
- OMIM
- 605885
- Ensembl
- ENSG00000092421
- UniProt/Swiss-Prot
- A0A0A0MQU6_HUMAN
- Entrez Gene
- 57556
- UniGene
- 156967
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- smp-1
- Danio rerio
- CABZ01112804.2
- Drosophila melanogaster
- Sema-1b
- Drosophila melanogaster
- Sema-1a
- Mus musculus
- Sema6a
- Rattus norvegicus
- Sema6a
In other databases
- CellAge gene expression
- This gene is present as SEMA6A
Studies (1)
Significant/Non-significant: 1/0
- Longevity Association
- Significant
- Population
- American (Caucasian)
- Study Design
- Genome-wide association study in 801 centenarians and 914 healthy controls
- Conclusions
- 281 SNPs were found to discriminate between cases and controls
- Indentifier
- rs10055012
- Reference