LongevityMap Gene
Gene details
- HGNC symbol
- PANDAR
- Aliases
- PANDA
- Common name
- promoter of CDKN1A antisense DNA damage activated RNA
- Description
- Cytogenetic Location
- 6p21.2
- UCSC Genome Browser
- View 6p21.2 on the UCSC genome browser
- OMIM
- 617179
- Ensembl
- ENSG00000281450
- UniProt/Swiss-Prot
- Entrez Gene
- 101154753
- UniGene
- 741557
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
No homologs found
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Italian
- Study Design
- 30 SNPs were identified by sequencing the promoter and exons of p21 in ten individuals over 90 years old. Then the frequency of 41 p21 SNPs between 184 centenarians and 184 younger subjects in the Italian population were compared.
- Conclusions
- Rare alleles of two exon-derived SNPs, rs1801270 and rs1059234, were significantly under-represented among the centenarians; no significant differences were found for 39 non-exonic SNPs
- Indentifier
- rs4711459
- Reference