LongevityMap Gene
Gene details
- HGNC symbol
- OR5F2P
- Aliases
- Common name
- olfactory receptor family 5 subfamily F member 2 pseudogene
- Description
- Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
- Cytogenetic Location
- 11q12.1
- UCSC Genome Browser
- View 11q12.1 on the UCSC genome browser
- OMIM
- Ensembl
- UniProt/Swiss-Prot
- Entrez Gene
- 81194
- UniGene
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
No homologs found
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- American, English, Irish
- Study Design
- 10 late-onset Alzheimer's disease genes were tested for association with human aging in the dataset (1385 samples with documented age at death, age range: 58–108 years; mean age at death: 80.2 years) using the most significant SNPs found in the previous studies. A set of 41 tentative SNPs span the genome were identified in this study.
- Conclusions
- Some signals were at best tentative but may merit study in larger sample sets
- Indentifier
- rs7952321
- Reference