LongevityMap Gene
Gene details
- HGNC symbol
- MYLK4
- Aliases
- SgK085
- Common name
- myosin light chain kinase family member 4
- Description
- Cytogenetic Location
- 6p25.2
- UCSC Genome Browser
- View 6p25.2 on the UCSC genome browser
- OMIM
- Ensembl
- ENSG00000145949
- UniProt/Swiss-Prot
- MYLK4_HUMAN
- Entrez Gene
- 340156
- UniGene
- 127830
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- ZC373.4
- Danio rerio
- mylk4a
- Danio rerio
- mylk4b
- Mus musculus
- Mylk4
- Rattus norvegicus
- Mylk4
- Rattus norvegicus
- Mylk4
- Saccharomyces cerevisiae
- MEK1
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- European
- Study Design
- Meta-analysis of genome-wide association studies of survival and survival free of major disease or death. In total, there were 25,007 participants over 55 years of age and followed-up for over 10 years for mortality and over 8 years for event-free survival.
- Conclusions
- No SNP was significantly associated with mortality after correcting for multiple testing, but 14 independent SNPs were associated with time to death at a suggestive threshold
- Indentifier
- rs17291546
- Reference