LongevityMap Gene
Gene details
- HGNC symbol
- MDGA2
- Aliases
- MAMDC1; c14_5286
- Common name
- MAM domain containing glycosylphosphatidylinositol anchor 2
- Description
- Cytogenetic Location
- 14q21.3
- UCSC Genome Browser
- View 14q21.3 on the UCSC genome browser
- OMIM
- 611128
- Ensembl
- ENSG00000139915
- UniProt/Swiss-Prot
- MDGA2_HUMAN
- Entrez Gene
- 161357
- UniGene
- 436380
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Italian
- Study Design
- Genome-wide association study on 410 long-living individuals (age range, 90–109 years) and 553 young control individuals (age range, 18–48 years) using 318,237 SNPs. An independent population with 116 long-lived individuals and 160 controls was used for replication purposes.
- Conclusions
- A total of 67 SNPs were identified with an indication of potentially being associated with longevity (p < 1 × 10−4), though 66 were not further validated
- Indentifier
- rs4594173
- Reference