LongevityMap Gene

Gene details

HGNC symbol
MAN2C1 
Aliases
MANA; MANA1; MAN6A8 
Common name
mannosidase alpha class 2C member 1 
Description
Cytogenetic Location
15q24.2
UCSC Genome Browser
View 15q24.2 on the UCSC genome browser
OMIM
154580
Ensembl
ENSG00000140400
UniProt/Swiss-Prot
A0A140VJN9_HUMAN
Entrez Gene
4123
UniGene
26232
1000 Genomes
1000 Genomes

Homologs in model organisms

Danio rerio
man2c1
Mus musculus
Man2c1
Rattus norvegicus
Man2c1
Saccharomyces cerevisiae
AMS1
Schizosaccharomyces pombe
ams1

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
Danish
Study Design
592 SNPs from 77 genes involved in nine sub-processes were analyzed in 1089 long-lived and 736 middle-aged Danes. Then, a replicated study was carried out in a German cohort.
Conclusions
The results did not remain significant after correction. The findings drawn from the Danish cohort were not replicated in German samples.
Indentifier
rs4462560
Reference