LongevityMap Gene
Gene details
- HGNC symbol
- LRRC14
- Aliases
- LRRC14A
- Common name
- leucine rich repeat containing 14
- Description
- This gene encodes a leucine-rich repeat-containing protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
- Cytogenetic Location
- 8q24.3
- UCSC Genome Browser
- View 8q24.3 on the UCSC genome browser
- OMIM
- Ensembl
- ENSG00000160959
- UniProt/Swiss-Prot
- LRC14_HUMAN
- Entrez Gene
- 9684
- UniGene
- 459391
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Danio rerio
- si:ch73-174h16.4
- Mus musculus
- Lrrc14
- Rattus norvegicus
- Lrrc14
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Danish
- Study Design
- 592 SNPs from 77 genes involved in nine sub-processes were analyzed in 1089 long-lived and 736 middle-aged Danes. Then, a replicated study was carried out in a German cohort.
- Conclusions
- The results did not remain significant after correction. The findings drawn from the Danish cohort were not replicated in German samples.
- Indentifier
- rs4244612
- Reference