LongevityMap Gene
Gene details
- HGNC symbol
- HYKK
- Aliases
- AGPHD1
- Common name
- hydroxylysine kinase
- Description
- Cytogenetic Location
- 15q25.1
- UCSC Genome Browser
- View 15q25.1 on the UCSC genome browser
- OMIM
- 614681
- Ensembl
- ENSG00000188266
- UniProt/Swiss-Prot
- HYKK_HUMAN
- Entrez Gene
- 123688
- UniGene
- 307962
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Danio rerio
- hykk.2
- Danio rerio
- hykk.1
- Drosophila melanogaster
- CG31751
- Mus musculus
- Hykk
- Rattus norvegicus
- Hykk
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Dutch
- Study Design
- A set of alleles associated with age-related diseases was tested for association with human longevity in 723 nonagenarian siblings and 721 unrelated younger controls plus 979 singleton individuals >85 years of age and 1,167 younger controls
- Conclusions
- No differences were observed in disease risk allele frequency between long-lived individuals and controls. No individual allele was significantly associated with survival to old age after controlling for multiple testing.
- Indentifier
- rs8034191
- Reference