LongevityMap Gene

Gene details

HGNC symbol
HMCN2 
Aliases
 
Common name
hemicentin 2 
Description
Cytogenetic Location
9q34.11
UCSC Genome Browser
View 9q34.11 on the UCSC genome browser
OMIM
Ensembl
ENSG00000148357
UniProt/Swiss-Prot
Entrez Gene
256158
UniGene
32194
1000 Genomes
1000 Genomes

Homologs in model organisms

Caenorhabditis elegans
him-4
Danio rerio
hmcn2
Mus musculus
Hmcn2

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
Italian
Study Design
Genome-wide association study on 410 long-living individuals (age range, 90–109 years) and 553 young control individuals (age range, 18–48 years) using 318,237 SNPs. An independent population with 116 long-lived individuals and 160 controls was used for replication purposes.
Conclusions
A total of 67 SNPs were identified with an indication of potentially being associated with longevity (p < 1 × 10−4), though 66 were not further validated
Indentifier
rs4740391
Reference