LongevityMap Gene

Gene details

HGNC symbol
GRAMD1B 
Aliases
 
Common name
GRAM domain containing 1B 
Description
Cytogenetic Location
11q24.1
UCSC Genome Browser
View 11q24.1 on the UCSC genome browser
OMIM
Ensembl
ENSG00000023171
UniProt/Swiss-Prot
A0A024R3M2_HUMAN
Entrez Gene
57476
UniGene
144725
1000 Genomes
1000 Genomes

Homologs in model organisms

Danio rerio
gramd1ba
Danio rerio
GRAMD1B (1 of many)
Drosophila melanogaster
CG34394
Mus musculus
Gramd1b
Rattus norvegicus
Gramd1b
Saccharomyces cerevisiae
856480
Saccharomyces cerevisiae
850501
Saccharomyces cerevisiae
850761
Saccharomyces cerevisiae
YSP2

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
European
Study Design
Meta-analysis of genome-wide association studies of survival and survival free of major disease or death. In total, there were 25,007 participants over 55 years of age and followed-up for over 10 years for mortality and over 8 years for event-free survival.
Conclusions
No SNP was significantly associated with mortality after correcting for multiple testing, but 14 independent SNPs were associated with time to death at a suggestive threshold
Indentifier
rs1274214
Reference