LongevityMap Gene
Gene details
- HGNC symbol
- FRYL
- Aliases
- MOR2; AF4p12; KIAA0826
- Common name
- FRY like transcription coactivator
- Description
- Cytogenetic Location
- 4p11
- UCSC Genome Browser
- View 4p11 on the UCSC genome browser
- OMIM
- Ensembl
- ENSG00000075539
- UniProt/Swiss-Prot
- B3KXG5_HUMAN
- Entrez Gene
- 285527
- UniGene
- 595553
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- sax-2
- Danio rerio
- fryl
- Drosophila melanogaster
- fry
- Mus musculus
- Fryl
- Rattus norvegicus
- Fryl
- Saccharomyces cerevisiae
- TAO3
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Italian
- Study Design
- Genome-wide association study on 410 long-living individuals (age range, 90–109 years) and 553 young control individuals (age range, 18–48 years) using 318,237 SNPs. An independent population with 116 long-lived individuals and 160 controls was used for replication purposes.
- Conclusions
- A total of 67 SNPs were identified with an indication of potentially being associated with longevity (p < 1 × 10−4), though 66 were not further validated
- Indentifier
- rs2354314
- Reference