LongevityMap Gene

Gene details

HGNC symbol
FAM49B 
Aliases
L1; BM-009 
Common name
family with sequence similarity 49 member B 
Description
Cytogenetic Location
8q24.21
UCSC Genome Browser
View 8q24.21 on the UCSC genome browser
OMIM
Ensembl
ENSG00000153310
UniProt/Swiss-Prot
A0A024R9G4_HUMAN
Entrez Gene
51571
UniGene
126941
1000 Genomes
1000 Genomes

Homologs in model organisms

Caenorhabditis elegans
R07G3.8
Danio rerio
fam49bb
Drosophila melanogaster
CG32066
Mus musculus
Fam49b
Rattus norvegicus
Fam49b

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
Italian
Study Design
Genome-wide association study on 410 long-living individuals (age range, 90–109 years) and 553 young control individuals (age range, 18–48 years) using 318,237 SNPs. An independent population with 116 long-lived individuals and 160 controls was used for replication purposes.
Conclusions
A total of 67 SNPs were identified with an indication of potentially being associated with longevity (p < 1 × 10−4), though 66 were not further validated
Indentifier
rs10956502
Reference