LongevityMap Gene
Gene details
- HGNC symbol
- FAM49B
- Aliases
- L1; BM-009
- Common name
- family with sequence similarity 49 member B
- Description
- Cytogenetic Location
- 8q24.21
- UCSC Genome Browser
- View 8q24.21 on the UCSC genome browser
- OMIM
- Ensembl
- ENSG00000153310
- UniProt/Swiss-Prot
- A0A024R9G4_HUMAN
- Entrez Gene
- 51571
- UniGene
- 126941
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- R07G3.8
- Danio rerio
- fam49bb
- Drosophila melanogaster
- CG32066
- Mus musculus
- Fam49b
- Rattus norvegicus
- Fam49b
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Italian
- Study Design
- Genome-wide association study on 410 long-living individuals (age range, 90–109 years) and 553 young control individuals (age range, 18–48 years) using 318,237 SNPs. An independent population with 116 long-lived individuals and 160 controls was used for replication purposes.
- Conclusions
- A total of 67 SNPs were identified with an indication of potentially being associated with longevity (p < 1 × 10−4), though 66 were not further validated
- Indentifier
- rs10956502
- Reference