LongevityMap Gene
Gene details
- HGNC symbol
- EIF4E3
- Aliases
- eIF-4E3; eIF4E-3
- Common name
- eukaryotic translation initiation factor 4E family member 3
- Description
- EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).[supplied by OMIM, Mar 2008]
- Cytogenetic Location
- 3p13
- UCSC Genome Browser
- View 3p13 on the UCSC genome browser
- OMIM
- 609896
- Ensembl
- ENSG00000163412
- UniProt/Swiss-Prot
- IF4E3_HUMAN
- Entrez Gene
- 317649
- UniGene
- 581355
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
Studies (1)
Significant/Non-significant: 1/0
- Longevity Association
- Significant
- Population
- American (Caucasian)
- Study Design
- Genome-wide association study in 801 centenarians and 914 healthy controls
- Conclusions
- 281 SNPs were found to discriminate between cases and controls
- Indentifier
- rs12629971
- Reference