LongevityMap Gene
Gene details
- HGNC symbol
- CD33
- Aliases
- p67; SIGLEC3; SIGLEC-3
- Common name
- CD33 molecule
- Description
- Cytogenetic Location
- 19q13.41
- UCSC Genome Browser
- View 19q13.41 on the UCSC genome browser
- OMIM
- 159590
- Ensembl
- ENSG00000105383
- UniProt/Swiss-Prot
- CD33_HUMAN
- Entrez Gene
- 945
- UniGene
- 83731
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Danio rerio
- si:dkey-24p1.7
- Mus musculus
- Siglecf
- Rattus norvegicus
- Siglec5
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- American, English, Irish
- Study Design
- 10 late-onset Alzheimer's disease genes were tested for association with human aging in the dataset (1385 samples with documented age at death, age range: 58–108 years; mean age at death: 80.2 years) using the most significant SNPs found in the previous studies. A set of 41 tentative SNPs span the genome were identified in this study.
- Conclusions
- Apart APOE, no variants appeared to be associated with aging with a genome-wide level of significance
- Indentifier
- rs3865444
- Reference