LongevityMap Gene
Gene details
- HGNC symbol
- CASC21
- Aliases
- CARLo-2; LINC01244
- Common name
- cancer susceptibility 21 (non-protein coding)
- Description
- Cytogenetic Location
- 8q24.21
- UCSC Genome Browser
- View 8q24.21 on the UCSC genome browser
- OMIM
- Ensembl
- UniProt/Swiss-Prot
- Entrez Gene
- 103021164
- UniGene
- 571531
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
No homologs found
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Dutch
- Study Design
- Genome-wide association study in 403 unrelated nonagenarians from long-living families and 1670 younger controls. Strongest candidates were then investigated in a meta-analysis of 4149 nonagenarian cases and 7582 younger controls.
- Conclusions
- No SNP reached significance in the GWAS but 62 SNPs, many in genes, had an indicative association with survival into old age. Of these 62 SNPs then studied in the meta-analysis, 61 were not significant.
- Indentifier
- rs11776260
- Reference