LongevityMap Gene
Gene details
- HGNC symbol
- CAMK1
- Aliases
- CAMKI
- Common name
- calcium/calmodulin dependent protein kinase I
- Description
- Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase. [provided by RefSeq, Jul 2008]
- Cytogenetic Location
- 3p25.3
- UCSC Genome Browser
- View 3p25.3 on the UCSC genome browser
- OMIM
- 604998
- Ensembl
- ENSG00000134072
- UniProt/Swiss-Prot
- B0YIY3_HUMAN
- Entrez Gene
- 8536
- UniGene
- 434875
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- cmk-1
- Danio rerio
- camk1b
- Danio rerio
- camk1a
- Drosophila melanogaster
- CaMKI
- Mus musculus
- Camk1
- Rattus norvegicus
- Camk1
- Saccharomyces cerevisiae
- CMK2
- Saccharomyces cerevisiae
- CMK1
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Danish
- Study Design
- 592 SNPs from 77 genes involved in nine sub-processes were analyzed in 1089 long-lived and 736 middle-aged Danes. Then, a replicated study was carried out in a German cohort.
- Conclusions
- The results did not remain significant after correction. The findings drawn from the Danish cohort were not replicated in German samples.
- Indentifier
- rs17252807
- Reference