LongevityMap Gene
Gene details
- HGNC symbol
- BTG3
- Aliases
- ANA; TOB5; TOFA; APRO4; TOB55; ANA/BTG3
- Common name
- BTG anti-proliferation factor 3
- Description
- The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Cytogenetic Location
- 21q21.1
- UCSC Genome Browser
- View 21q21.1 on the UCSC genome browser
- OMIM
- 605674
- Ensembl
- ENSG00000154640
- UniProt/Swiss-Prot
- BTG3_HUMAN
- Entrez Gene
- 10950
- UniGene
- 473420
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
In other databases
- CellAge
- This gene is present as BTG3
Studies (1)
Significant/Non-significant: 1/0
- Longevity Association
- Significant
- Population
- American (Caucasian)
- Study Design
- Genome-wide association study in 801 centenarians and 914 healthy controls
- Conclusions
- 281 SNPs were found to discriminate between cases and controls
- Indentifier
- rs9977638
- Reference