LongevityMap Gene

Gene details

HGNC symbol
BTG3 
Aliases
ANA; TOB5; TOFA; APRO4; TOB55; ANA/BTG3 
Common name
BTG anti-proliferation factor 3 
Description
The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Cytogenetic Location
21q21.1
UCSC Genome Browser
View 21q21.1 on the UCSC genome browser
OMIM
605674
Ensembl
ENSG00000154640
UniProt/Swiss-Prot
BTG3_HUMAN
Entrez Gene
10950
UniGene
473420
1000 Genomes
1000 Genomes

Homologs in model organisms

Danio rerio
btg3
Drosophila melanogaster
Tob
Mus musculus
Gm7334
Mus musculus
Btg3
Rattus norvegicus
Btg3

In other databases

CellAge
  • This gene is present as BTG3

Studies (1)

Significant/Non-significant: 1/0

Longevity Association
Significant
Population
American (Caucasian)
Study Design
Genome-wide association study in 801 centenarians and 914 healthy controls
Conclusions
281 SNPs were found to discriminate between cases and controls
Indentifier
rs9977638
Reference