LongevityMap Gene
Gene details
- HGNC symbol
- BPIFB4
- Aliases
- RY2G5; LPLUNC4; C20orf186; dJ726C3.5
- Common name
- BPI fold containing family B member 4
- Description
- Cytogenetic Location
- 20q11.21
- UCSC Genome Browser
- View 20q11.21 on the UCSC genome browser
- OMIM
- 615718
- Ensembl
- ENSG00000186191
- UniProt/Swiss-Prot
- BPIB4_HUMAN
- Entrez Gene
- 149954
- UniGene
- 38961
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Italian
- Study Design
- Genome-wide association study on 410 long-living individuals (age range, 90–109 years) and 553 young control individuals (age range, 18–48 years) using 318,237 SNPs. An independent population with 116 long-lived individuals and 160 controls was used for replication purposes.
- Conclusions
- A total of 67 SNPs were identified with an indication of potentially being associated with longevity (p < 1 × 10−4), though 66 were not further validated
- Indentifier
- rs2070325
- Reference