LongevityMap Gene

Gene details

HGNC symbol
ATCAY 
Aliases
CLAC; BNIP-H 
Common name
ATCAY, caytaxin 
Description
This gene encodes a neuron-restricted protein that contains a CRAL-TRIO motif common to proteins that bind small lipophilic molecules. Mutations in this gene are associated with cerebellar ataxia, Cayman type. [provided by RefSeq, Jul 2008]
Cytogenetic Location
19p13.3
UCSC Genome Browser
View 19p13.3 on the UCSC genome browser
OMIM
608179
Ensembl
ENSG00000167654
UniProt/Swiss-Prot
A0A0S2Z5T8_HUMAN
Entrez Gene
85300
UniGene
418055
1000 Genomes
1000 Genomes

Homologs in model organisms

Danio rerio
atcayb
Danio rerio
atcaya
Drosophila melanogaster
CG11593
Mus musculus
Atcay
Rattus norvegicus
Atcay

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
European
Study Design
Meta-analysis of genome-wide association studies of survival and survival free of major disease or death. In total, there were 25,007 participants over 55 years of age and followed-up for over 10 years for mortality and over 8 years for event-free survival.
Conclusions
No SNP was significantly associated with time to event after correcting for multiple testing, but 8 independent SNPs predicted event-free survival at a suggestive threshold
Indentifier
rs10412199
Reference