LongevityMap Gene
Gene details
- HGNC symbol
- ATCAY
- Aliases
- CLAC; BNIP-H
- Common name
- ATCAY, caytaxin
- Description
- This gene encodes a neuron-restricted protein that contains a CRAL-TRIO motif common to proteins that bind small lipophilic molecules. Mutations in this gene are associated with cerebellar ataxia, Cayman type. [provided by RefSeq, Jul 2008]
- Cytogenetic Location
- 19p13.3
- UCSC Genome Browser
- View 19p13.3 on the UCSC genome browser
- OMIM
- 608179
- Ensembl
- ENSG00000167654
- UniProt/Swiss-Prot
- A0A0S2Z5T8_HUMAN
- Entrez Gene
- 85300
- UniGene
- 418055
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Danio rerio
- atcayb
- Danio rerio
- atcaya
- Drosophila melanogaster
- CG11593
- Mus musculus
- Atcay
- Rattus norvegicus
- Atcay
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- European
- Study Design
- Meta-analysis of genome-wide association studies of survival and survival free of major disease or death. In total, there were 25,007 participants over 55 years of age and followed-up for over 10 years for mortality and over 8 years for event-free survival.
- Conclusions
- No SNP was significantly associated with time to event after correcting for multiple testing, but 8 independent SNPs predicted event-free survival at a suggestive threshold
- Indentifier
- rs10412199
- Reference