LongevityMap Gene
Gene details
- HGNC symbol
- ANKUB1
- Aliases
- C3orf16
- Common name
- ankyrin repeat and ubiquitin domain containing 1
- Description
- Cytogenetic Location
- 3q25.1
- UCSC Genome Browser
- View 3q25.1 on the UCSC genome browser
- OMIM
- Ensembl
- ENSG00000206199
- UniProt/Swiss-Prot
- ANKUB_HUMAN
- Entrez Gene
- 389161
- UniGene
- 665988
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Dutch
- Study Design
- Genome-wide association study in 403 unrelated nonagenarians from long-living families and 1670 younger controls. Strongest candidates were then investigated in a meta-analysis of 4149 nonagenarian cases and 7582 younger controls.
- Conclusions
- No SNP reached significance in the GWAS but 62 SNPs, many in genes, had an indicative association with survival into old age. Of these 62 SNPs then studied in the meta-analysis, 61 were not significant.
- Indentifier
- rs4681554
- Reference